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Improving Contact Prediction along Three Dimensions

Figure 8

Mispredictions.

Among the 729 proteins plotted in Figure 3 there is less than 5% prominent outliers where plmDCA (model with no gap parameters) clearly does better than gplmDCA (model with gap parameters). Upper row depicts gplmDCA predictions, lower — plmDCA20. Left panels show the contact maps of protein S, where gplmDCA wrongly predicts a number of spurious contacts between N- and C- terminii Right panels, contact maps of transcription elongation factor Spt4. The prediction artifacts of gplmDCA are not detectable in plmDCA20 predictions. For further discussion, see main text.

Figure 8

doi: https://doi.org/10.1371/journal.pcbi.1003847.g008