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The Dynamics of DNA Methylation Covariation Patterns in Carcinogenesis

Figure 6

DNA methylation changes of DNB markers during cervical carcinogenesis.

Heatmap depicts the DNAm levels of the 91 CpGs making up the DNB module (LBC1-B) across six stagtes in cervical carcinogenesis, as indicated. In each disease stage, samples have been ordered according to the average fraction of the 91 CpGs that exhibit a methylation beta-value larger than 0.2 (see upper panel).

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1003709.g006