A Network Characteristic That Correlates Environmental and Genetic Robustness
Figure 3
Correlation between robustness to input and parameter perturbations within 3-node, 5-node, 15-node, and 30-node TR networks.
and are measures of robustness of a topology to input and parameter perturbations, respectively, computed from the average over TR networks. Topologies with a low fraction of TR networks (less than 2.3%) are not included. The linear regression for all sizes (3-node, 5-node, 15-node, and 30-node) shows a significant (p<0.0001) correlation between and . (A) 3-node topologies: slope = 0.62 (N = 2445, r = 0.57). (B) 5-node topologies: slope = 0.64 (N = 7847, r = 0.40). (C) 10-node topologies: slope = 0.76 (N = 18300, r = 0.33). (D) 15-node topologies: slope = 0.80 (N = 19264, r = 0.35). (E) 30-node topologies: slope = 0.96 (N = 16587, r = 0.41).