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Beyond GLMs: A Generative Mixture Modeling Approach to Neural System Identification

Figure 1

Illustration of the spike-triggered mixture model (STM).

A. A sigmoidal nonlinearity is applied to a log-likelihood ratio of two mixtures of Gaussians to determine the firing rate of the model, which is then used to generate spikes. B. By making a naive Bayes assumption, additional information and measurements such as interspike interval distributions can easily be incorporated into the model in the form of additional log-likelihood ratios.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1003356.g001