An Integrated Regulatory Network Reveals Pervasive Cross-Regulation among Transcription and Splicing Factors
Figure 5
The GO term “RNA splicing” is significantly enriched among experimentally verified targets of SFs.
GO enrichment for CLIP targets of four SFs, SF2/ASF (HEK 293 cells), FOX2 (Embryonic Stem Cells), PTB (HeLa cells) and QKI (HEK 293 cells) for two GO annotation terms: transcription factor activity (blue) and RNA splicing (red). Bar height represents the statistical significance shown by–log10 of the P-value. The dashed line marks the level of statistical significance (p-value = 5e-2).