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Reconstruction of Genome-Scale Active Metabolic Networks for 69 Human Cell Types and 16 Cancer Types Using INIT

Figure 3

Gene content comparison between our hepatocyte model and HepatoNet1.

The Venn diagram shows the overlap in terms of included genes between three models. The blue, green and red squares represent iHuman1512, our hepatocyte model iHepatocyte1154 and HepatoNet1, respectively. The distribution of evidence scores of each section of the Venn diagram is plotted. The HPA evidence scores are illustrated as red, light, medium and dark green represent negative, weak moderate and strong expression, respectively. The transcriptome evidence scores (GeneX) are illustrated as red, light, medium and dark blue representing low, medium and high expression, respectively. No evidence (NE) is illustrated as grey color.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1002518.g003