A Mathematical Framework for Estimating Pathogen Transmission Fitness and Inoculum Size Using Data from a Competitive Mixtures Animal Model
Figure 2
Representative curves for four shape parameters, .
We assume and so
. We label the curves by the relative “transmission fitness” of strain
compared to strain
,
. We have
(
) (solid line): strain
's transmission fitness is 10% that of strain
,
(
) (dashed line): strain
's transmission fitness is 90% that of strain
,
(
) (dotted line): strain
and strain
have equal transmission fitness, and
(
) (dash-dotted line): strain
's transmission fitness is 10 times that of strain
.