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Polyamine Sharing between Tubulin Dimers Favours Microtubule Nucleation and Elongation via Facilitated Diffusion

Figure 8

Scaling properties and nucleus size in the presence of spermidine.

Initial slope of log [(I(t)/I(∞)] versus tubulin concentration. This slope is an interesting indicator of the number of tubulin dimers in the critical nuclei. The mean slope over tubulin concentrations is similar with or without spermidine, 2.36 and 2.32 respectively. Spermidine may then not affect the critical size of the nucleus but this remains to be demonstrated with a valid theory. Inset: examples of log–log plot of [(I(t)/I(∞)]. The slopes were extracted at early times when the curves display a straight line.

Figure 8

doi: https://doi.org/10.1371/journal.pcbi.1000255.g008