Malleable Machines in Transcription Regulation: The Mediator Complex
Figure 6
Location of α-MoRFs predicted by the PONDR VL-XT algorithm in Med7 and Med8 subunits of Saccharomyces cerevisiae in (A) Med7/Med21 (1yke) [27] and (B) Med8/Med18/Med20 (2hzs) [28] complexes.
The recognition motifs in Med7 (195–212) and Med8 (193–210) that are biased for an α-helical conformation in the bound state are shown by red.