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Polar or Apolar—The Role of Polarity for Urea-Induced Protein Denaturation

Figure 3

Solvent accessible surface area of the protein in all simulations.

Blue: water, orange: urea_50%, magenta: urea_75%, green: urea_100%, black: urea_150%. The lines show traces smoothed by a running average over 500 ps. The histogram in the right panel shows the frequency of the respective SAS.

doi: https://doi.org/10.1371/journal.pcbi.1000221.g003