Control of Membrane Fusion Mechanism by Lipid Composition: Predictions from Ensemble Molecular Dynamics
Figure 2
Starting Structures for Vesicles at Three Different Lipid Compositions
(A) Pure POPE vesicles.
(B) Vesicles composed of a 1:1 POPC:POPE mixture.
(C) Vesicles composed of a 2:1 POPC:POPE mixture.
POPE lipids are rendered in pink, POPC in purple. Rendered surfaces represent the solvent-accessible surface of the vesicle; spheres represent the phosphate groups of the vesicle inner leaflet lipids. Vesicles are linked by a single crosslinker molecule.