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A Nucleosome-Guided Map of Transcription Factor Binding Sites in Yeast

Figure 3

Distribution of S℘N℘, S℘D℘N℘, and S℘D℘N℘ in the Sequence-Set for Leu3 Profiled in YPD

The distribution of scores over each unique 10-mer occurring in the Leu3_YPD sequence-set shown as a percentile plot (on the left) and as a histogram (on the right) computed according to: (A) S℘N℘ (averaged over each 10-mer) using predictions from computational model of Segal et al., (B) S℘D℘N℘ using predictions from computational model of Segal et al., and (C) S℘D℘N℘ using low-resolution nucleosome data from Lee et al. The three colored dots marked on each figure indicate the positions of the only three 10-mers matching the Leu3 motif CCGGNNCCGG present in Leu3_YPD. The red dot corresponds to CCGGTACCGG (see text). The mass to the right of the dots in each graph reveals the fraction of 10-mers scoring higher.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.0030215.g003