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A Macaque's-Eye View of Human Insertions and Deletions: Differences in Mechanisms

Figure 2

Scatterplots of 1-Mb Windows across the Human Genome (Lowess Smooths Are Superimposed on Each Plot as Visual Aids)

(A) Insertion versus deletion rates. (B) Indel rates versus divergence. (C) Indel rates versus GC content. In all three instances, the quadratic fits (p < 10−15 for (A–C)) explained the data better than linear fits. Empty circles, chromosome X windows; filled circles, autosomal windows; purple circles, windows skewed toward insertions; green circles, windows skewed toward deletions; pink circles, windows skewed toward indels; blue circles, windows skewed toward nucleotide substitutions.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.0030176.g002