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PERIOD–TIMELESS Interval Timer May Require an Additional Feedback Loop

Figure 5

Detailed Model Black Box

The per/tim loop of the detailed mathematical model of Drosophila circadian rhythmicity, a possible mechanism underlying the black box in Figure 1. Only one type of monomeric TIM and no monomeric DBT species were explicitly represented in the model. See Materials and Methods for a list of model equations.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.0030154.g005