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Emergent Dynamics of Thymocyte Development and Lineage Determination

Figure 1

A Snapshot of the Simulated Thymus at Run Time

(A) Different colors stand for different stages during thymocyte selection. The legend box shows the different developmental stages and their corresponding colors.

(B) Different icons beneath the figure stand for different tools for the control and the visualization of the simulation. The tools include the ability to zoom into parts of the visualization, show and hide the two tiers of the simulation, highlight interacting cells, display or hide chemokine gradients, display statistical information through real-time communication with Matlab, visualize apoptotic levels in real-time, initiate and stop a backtrack of a cell's migration, and more.

(A,B) In the lower right hand side, the elapsed time is displayed, together with a utility that enables the control of time progression.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.0030013.g001