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Targeted Molecular Dynamics Study of C-Loop Closure and Channel Gating in Nicotinic Receptors

Figure 1

Amino Acid Sequence of the Human α7 Nicotinic Receptor Aligned with AChBP and the Torpedo Receptor

Sequence numbering corresponds to the human α7 receptor. Positions colored red and green are highly conserved, and have been implicated in the channel gating mechanism.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.0020134.g001