Sampling Realistic Protein Conformations Using Local Structural Bias
Figure 2
Conditional Dependency Graph of FB5–HMM
Squares represent discrete nodes, circles represent the FB5 node with unit vector output. The arrows indicate conditional dependencies. Three slices are shown, corresponding to three consecutive amino acid positions. A possible set of node values is shown in color (v1, v2, and v3 are unit vectors). The hidden node sequence (34,34,3) corresponds to two C-terminal positions of an α-helix, followed by a coil residue.
A, amino acid node; F, FB5 node; H, hidden node; S, secondary structure node.