Circadian Transcription Contributes to Core Period Determination in Drosophila
Figure 5
Increase of Clk Copy Number Shortens the Circadian Clock
(A) Behavioral analysis of fly strains with one, two, or three doses of a Clk transgene. Transgenes in the second and third chromosome were used. All of the flies assayed are wild type for the endogenous Clk locus.
(B) Luciferase recordings from control (yw) and flies carrying two doses of a Clk transgene utilizing the tim-luc reporter. Light timing is indicated by alternating white and gray background areas, with white representing the illuminated interval of the LD condition (ZT0–12) and gray representing the dark period (ZT12–24). The results are the average of 13 (two copies of the Clk transgene) and 18 (control) pairs of fly wings.