A Mechanism Regulating the Onset of Sox2 Expression in the Embryonic Neural Plate
Figure 3
Expression of Chick Geminin during Normal Development and Its Regulation by FGF
(A–G) Geminin is expressed in the embryonic epiblast from pre-primitive streak stages (A). As the embryo develops, its expression becomes restricted to the neural plate, where it intensifies (B–G).
(H) An FGF-soaked bead up-regulates Geminin in the extra-embryonic epiblast (arrow); a control bead has been grafted on the contralateral side (arrowhead). Embryo stages as for Figure 2.