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A Role for PCNA Ubiquitination in Immunoglobulin Hypermutation

Figure 5

Ig Hypermutation of the PCNAK164R/K164R Clone

Ig light-chain sequence variation in the PCNAK164R/K164R clone. All sequence differences in the region from the first intron to the J-C intron are shown relative to the rearranged light-chain consensus sequence of the AIDRψV precursor clone. The position of complementary determining regions CDR1, CDR2, and CDR3 and that of Jλ are indicated.

Figure 5

doi: https://doi.org/10.1371/journal.pbio.0040366.g005