Abstract
We demonstrate rapid vibrational imaging based on sum frequency generation (SFG) microscopy with a collinear excitation geometry. Using the tunable picosecond pulses from a high-repetition-rate optical parametric oscillator, vibrationally selective imaging of collagen fibers is achieved with submicrometer lateral resolution. We furthermore show simultaneous SFG and second harmonic generation imaging to emphasize the compatibility of the microscope with other nonlinear optical modalities.
© 2011 Optical Society of America
Full Article | PDF ArticleMore Like This
Adam Hanninen, Ming Wai Shu, and Eric O. Potma
Biomed. Opt. Express 8(9) 4230-4242 (2017)
Chi Zhang, Joshua Jasensky, Chuan Leng, Chelsey Del Grosso, Gary D. Smith, Jonathan J. Wilker, and Zhan Chen
Opt. Lett. 39(9) 2715-2718 (2014)
Eun Seong Lee, Sang-Won Lee, Julie Hsu, and Eric O. Potma
Biomed. Opt. Express 5(7) 2125-2134 (2014)