A comparative study of arterial spin labeling and dynamic contrast-enhanced MRI of spinal bone marrow perfusion imagingChinese Full Text
XING Dong;ZHA Yun-fei;LI Qin-xiang;Department of Radiology,Renmin Hospital of Wuhan University;
Abstract: Objective:To analyse the correlation between arterial spin-labeling（ASL）and dynamic contrast-enhanced magnetic resonance imaging（DCE-MRI）in the measurement of spinal bone marrow（SBM）perfusion,in order to explore the feasibility of ASL in the measurement of SBM blood flow.Methods:ASL and DCE-MRI was performed on 54lumbar vertebral bodies from 27subjects.Each vertebral body was covered by one region of interest（ROI）and the original images were all reprocessed with Functool and Cinetool at AW 4.4workstation,respectively.The correlation between the blood flow on ASL（BFASL）and perfusion-related parameters（Ktrans,Kep,Ve）on DCE-MRI were evaluated using the Pearson correlation coefficient.Results:Blood flow on ASL（BFASL）showed a close correlation with Ktrans（r=0.646,P＜0.001）and Kep（r=0.387,P=0.004）,but showed no correlation with Ve（r=0.239,P=0.082）.Conclusion:As blood flow measurement on ASL is reliable and closely related with the parameters on DCE-MR,ASL is feasible for measuring SBM blood flow.
Keywords：
Magnetic resonance imaging; Perfusion; Arterial spin labeling; Dynamic contrast-enhancement; Spinal bone marrow;
- DOI：
10.13609/j.cnki.1000-0313.2014.03.026
- Series：
- Subject：
- Classification Code：
R445.2
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