Address reprint requests to: B Lawrence Riggs, MD Mayo Clinic Endocrine Research Unit 200 First Street SW, 5-194 Joseph Rochester, MN 55905, USA E-mail: Riggs.Lawrence@mayo.edu
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Abstract
Journal of Bone and Mineral Research, February 2005:20:177-184 (doi: 10.1359/JBMR.041114)
Drugs Used to Treat Osteoporosis: The Critical Need for a Uniform Nomenclature Based on Their Action on Bone Remodeling B Lawrence Riggs, 1 A Michael Parfitt2 1Endocrine Research Unit, Division of Endocrinology and Metabolism, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester Minnesota, USA; 2Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. There continues to be uncertainty about the classification of available drugs for treating osteoporosis. We find that grouping them into anti-catabolic and anabolic classes based on the mechanisms of their action on bone remodeling and fracture reduction removes ambiguities and provides a relatively straightforward classification. Cited byMonique E Arlot, Yebin Jiang, Harry K Genant, Jenny Zhao, Brigitte Burt-Pichat, Jean-Paul Roux, Pierre D Delmas and Pierre J Meunier. (2008) Histomorphometric and μCT Analysis of Bone Biopsies From Postmenopausal Osteoporotic Women Treated With Strontium Ranelate. Journal of Bone and Mineral Research 23:2, 215-222 Online publication date: 1-Feb-2008. Abstract | Full Text | Printable PDF (356 KB) Negin Amanat, Michelle McDonald, Craig Godfrey, Lynne Bilston and David Little. (2007) Optimal Timing of a Single Dose of Zoledronic Acid to Increase Strength in Rat Fracture Repair. Journal of Bone and Mineral Research 22:6, 867-876 Online publication date: 1-Jun-2007. Abstract | Full Text | Printable PDF (1453 KB) Sherri-Ann M Burnett, Samantha C Gunawardene, F Richard Bringhurst, Harald Jüppner, Hang Lee and Joel S Finkelstein. (2006) Regulation of C-Terminal and Intact FGF-23 by Dietary Phosphate in Men and Women. Journal of Bone and Mineral Research 21:8, 1187-1196 Online publication date: 1-Aug-2006. Abstract | Full Text | Printable PDF (1044 KB) Yanfei L Ma, Qingqiang Zeng, David W Donley, Louis-Georges Ste-Marie, J Christopher Gallagher, Gail P Dalsky, Robert Marcus and Erik Fink Eriksen. (2006) Teriparatide Increases Bone Formation in Modeling and Remodeling Osteons and Enhances IGF-II Immunoreactivity in Postmenopausal Women With Osteoporosis*. Journal of Bone and Mineral Research 21:6, 855-864 Online publication date: 1-Jun-2006. Abstract | Full Text | Printable PDF (5694 KB) Hua Zhu Ke, D Todd Crawford, Hong Qi, Hollis A Simmons, Thomas A Owen, Vishwas M Paralkar, Mei Li, Bihong Lu, William A Grasser, Kimberly O Cameron, Bruce A Lefker, Paul DaSilva-Jardine, Dennis O Scott, Qing Zhang, Xiao Yan Tian, Webster SS Jee, Thomas A Brown and David D Thompson. (2006) A Nonprostanoid EP4 Receptor Selective Prostaglandin E2 Agonist Restores Bone Mass and Strength in Aged, Ovariectomized Rats. Journal of Bone and Mineral Research 21:4, 565-575 Online publication date: 1-Apr-2006. Abstract | Full Text | Printable PDF (2415 KB) B Lawrence Riggs, L Joseph Melton III, Richard A Robb, Jon J Camp, Elizabeth J Atkinson, Ann L Oberg, Peggy A Rouleau, Cynthia H McCollough, Sundeep Khosla and Mary L Bouxsein. (2006) Population-Based Analysis of the Relationship of Whole Bone Strength Indices and Fall-Related Loads to Age- and Sex-Specific Patterns of Hip and Wrist Fractures. Journal of Bone and Mineral Research 21:2, 315-323 Online publication date: 1-Feb-2006. Abstract | Full Text | Printable PDF (113 KB) Sundeep Khosla, B Lawrence Riggs, Elizabeth J Atkinson, Ann L Oberg, Lisa J McDaniel, Margaret Holets, James M Peterson and L Joseph Melton III. (2006) Effects of Sex and Age on Bone Microstructure at the Ultradistal Radius: A Population-Based Noninvasive In Vivo Assessment. Journal of Bone and Mineral Research 21:1, 124-131 Online publication date: 1-Jan-2006. Abstract | Full Text | Printable PDF (1671 KB) David G Little, Michelle McDonald, Rick Bransford, Craig B Godfrey and Negin Amanat. (2005) Manipulation of the Anabolic and Catabolic Responses With OP-1 and Zoledronic Acid in a Rat Critical Defect Model. Journal of Bone and Mineral Research 20:11, 2044-2052 Online publication date: 1-Nov-2005. Abstract | Full Text | Printable PDF (563 KB) |
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