Chinese Journal of Radiological Health. 2014, (01)

A Comparison of Doses for Conventional and Intensity Modulated Radiation Therapy after Breast- conserving Operation in Early- stage Breast CancerChinese Full Text

TIAN Lei;LI Hui - cheng;CHI Qi;LU Xue;LIU Xiao - lan;WANG Tie - jun;The Department of Radiotherapy of the Second Affiliated Hospital of Jilin University;The Separtment of radiotherapy of General Hospital of Faw;

Abstract: Objective To compare the dosimetry distribution between conventional radiotherapy（ CRT） and intensity modulated radiation therapy（ IMRT） after breast- conserving surgery in early- stage breast cancer,and provide evidence for the application of IMRT in patients. Methods Twelve patients with early- stage breast cancer,who received breast conserving surgery,were selected in this study. CRT and IMRT plans with prescribed dose of 50 Gy /25 f were designed for each patient. The Dose volume histograms（ DVHs） were used to evaluate the dosimetric distribution of the plan target volume（ PTV） and the organs at risk（ OARs） between the two plans. Results The V95%of PTV was similar in the two plans（ 98. 22% vs 98. 76%）; The V105%、V110%of PTV in IMRT plans was 12. 86% 、1. 02% versus 44. 56% 、6. 37% in CRT plans（ P ＜ 0. 05）; The conformity index（ CI） in IMRT plans was increased from 0. 55 to 0. 68,while the homogeneity index（ HI） was decreased from 1. 15 to 1. 09（ P ＜ 0. 05）. Compared to CRT plans,the V30and V20of the ipsilateral lung in IMRT plans was reduced by 3. 68% and 5. 75%,the mean lung dose（ MLD） was decreased from 9. 24 Gy to 7. 12 Gy（ P ＜ 0. 05）; In the left side patients,the V30、V40and V50of the heart in IMRT plans was reduced by 5. 99% 、5. 68% and 1. 68%,respectivly（ P ＜ 0. 05）. Conclusion Compared to CRT,IMRT decreased the high dose volume and improved the dose homogeneity with a satisfactory target coverage and effectively reduced the radiation dose for normal organs such as the heart and lungs.

Keywords：

Breast Cancer; Breast-Conserving Surgery; Conventional Radiotherapy; Intensity Modulated Eadiation Thera-py;

DOI：
10.13491/j.cnki.issn.1004-714x.2014.01.022
Series：
Subject：
Classification Code：
R814.2

Mobile Reading

Read on your phone instantly

Step 1
Scan QR Codes

"Mobile CNKI-CNKI Express" App

Step 2
Open“CNKI Express”

and click the scan icon in the upper left corner of the homepage.

Step 3
Scan QR Codes

Read this article on your phone.
HTML
CAJ Download
PDF Download

Contents

A Comparison of Doses for Conventional and Intensity Modulated Radiation Therapy after Breast- conserving Operation in Early- stage Breast CancerChinese Full Text

TIAN Lei;LI Hui - cheng;CHI Qi;LU Xue;LIU Xiao - lan;WANG Tie - jun;The Department of Radiotherapy of the Second Affiliated Hospital of Jilin University;The Separtment of radiotherapy of General Hospital of Faw;

Read on your phone instantly

Citation Network

Related Literature