Chinese Journal of Antibiotics. 2011, (03) Core

Advances on biosynthesis of anthracycline antibiotics by Streptomyces peucetiusChinese Full Text

He Jian-wu,Chen Qi-hui,Liu Zhu-xiang,Zhuang Da-chun,Huang Ke and Chen Yi-guang(Key Laboratory for Conservation and Utilization of Plant Resources, College of Biology and Environment Science,Jishou University,Jishou 416000)

Abstract: Anthracyclines antibiotics have been a preferred clinical drug,attributable to their ability to exhibit good effectiveness in the treatment of a number of cancers,such as acute nonlymphocytic leukemia,malignant lymphoma,sarcoma and breast cancer.Streptomyces peucetius is the best important species synthesizing anthracycline antibiotics（daunorubicin,doxorubicin,4’-pei-doxorubicin,4’-pei-daunorubicin,carminomycin,13-deoxocarminomycin,etc.）.Studies on the biosynthesis and pathway engineering of bioactive products by S.peucetius has been a hot point at home and abroad.The research advances on the biosynthesis of anthracyclines antibiotics by S.peucetius were summarized,and the development trend was also pointed out in this paper.

Keywords：

Streptomyces peucetius; Anthracyclines antibiotic; Biosynthesis; Pathway engineering;

DOI：
10.13461/j.cnki.cja.004737
Series：
Subject：
Classification Code：
R914;R96

Mobile Reading

Read on your phone instantly

Step 1
Scan QR Codes

"Mobile CNKI-CNKI Express" App

Step 2
Open“CNKI Express”

and click the scan icon in the upper left corner of the homepage.

Step 3
Scan QR Codes

Read this article on your phone.
HTML
CAJ Download
PDF Download

Contents

Advances on biosynthesis of anthracycline antibiotics by Streptomyces peucetiusChinese Full Text

He Jian-wu,Chen Qi-hui,Liu Zhu-xiang,Zhuang Da-chun,Huang Ke and Chen Yi-guang(Key Laboratory for Conservation and Utilization of Plant Resources, College of Biology and Environment Science,Jishou University,Jishou 416000)

Read on your phone instantly

Citation Network

Related Literature