Chinese Journal of Clinical Oncology and Rehabilitation. 2014, (05)

Effects of different doses of recombinant human erythropoietin in the treatment of malignant tumoranemiaChinese Full Text

LU Zhong;SHUI Yue;ZENG Ying;Pharmacy Department,The First People’s Hospital of Yibin City;Operation Room,The First People’s Hospital of Yibin City;Laboratory Department,The First People’s Hospital of Yibin City;

Abstract: Objective To investigate the effects of different doses of recombinant human erythropoietin for treating cancer anemia and provide reference for rational drug use. Methods 140 cases of cancer anemia based on the order of admission were equally divided into the treatment group and the control group,the control group were given subcutaneous recombinant human erythropoietin 50μ / kg,the treatment group were injected with the dose of 150μ / kg,3 times a week. 8 weeks of treatment in theboth groups. Results The total efficiency of the treatment group and the control group were 84. 3% and 67. 1% that there had significant difference compared（ P ＜ 0. 05）. Before treatment,hemoglobin and hematocrit values between the two groups contrasted the difference had not statistically significant,compared with the betweengroup had statistically significant difference after treatment（ P ＜ 0. 05）. The physiological function,ole limitations physiological function,emotional role limitations,vitality scores of the treatment group were significantly higher（ P ＜ 0. 05）. there were 2 patients in each group were high blood pressure and were improved by the use of antihypertensive drugs（ P ＞ 0. 05）. Conclusion Large doses of recombinant human erythropoietin for treating cancer anemia has better efficacy and can increase hemoglobin and hematocrit values, improve the quality of life and the safety is better.

Keywords：

Malignant tumor; Anemia; Recombinant human erythropoietin; Quality of life;

DOI：
10.13455/j.cnki.cjcor.2014.05.41
Series：
Subject：
Classification Code：
R730.5

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Effects of different doses of recombinant human erythropoietin in the treatment of malignant tumoranemiaChinese Full Text

LU Zhong;SHUI Yue;ZENG Ying;Pharmacy Department,The First People’s Hospital of Yibin City;Operation Room,The First People’s Hospital of Yibin City;Laboratory Department,The First People’s Hospital of Yibin City;

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