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Analysis of karyotype by G-banding for 1147 Chinese males with infertilityChinese Full Text

FENG Jiang-bin,LU Xue,ZHAO Hua,CHEN De-qing,LIU Qing-Jie.(Key Laboratory of Radiological Protection and Nuclear Emergency,China CDC;National Institute for Radiological Protection,China CDC,Beijing 100088,P.R.China)

Abstract: Objective: To study the relations between chromosome defects and male infertility.Methods: Chromosome preparations made from peripheral blood lymphocytes by conventional,G-banding technique 1147 cases of male infertiliey.Results: There are 97 cases with chromosome abnormalities which is 8.5% in all cases(97/1147).Eighty cases of sex chromosome abnormalities were detected,which account for 82.5% in total chromosomal abnormality.And 8 cases of chimera,1 case of sexual inversion,11 cases of translocation and 1 cases of inversion were found.Conclusion: Chromosome abnormality is very important etiology in male infertility.Chromosome karyotype analysis should be carried out routinely for male infertility.
  • DOI:

    10.13404/j.cnki.cjbhh.2013.05.025

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  • Classification Code:

    R698.2

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