Cattle encephalon glycoside and ignotin for patients with HIE:a systematic reviewChinese Full Text
CHEN Lu-jia;WANG Ling;WANG Chuan-wei;JIANG Xue-hua;Research Center for Clinical Pharmacy,West China School of Pharmacy,Sichuan University;
Abstract: OBJECTIVE To evaluate the effectiveness and safety of cattle encephalon glycoside and ignotin for patients with hypoxic ischemic encephalopathy(HIE).METHODS The Cochrane Library(Issue 1,2013),EMbase,PubMed,CBM, CNKI and VIP(from their inception to March2013)were searched for RCTs of cattle encephalon glycoside and ignotin for patients with HIE.Two reviewers independently retrieved RCTs according to the inclusion and exclusion criteria,assessed the methodological quality of included trials,and extracted data.The data analyses was performed by RevMan 5.16 software. RESULTS 19 RCTs involving 1 353 patients were ultimately identified.The results of Meta-analyses showed that effective rate of cattle encephalon glycoside and ignotin was superior to control group[OR=4.56,95%CI(3.29,6.34),P<0.01];the recovery time of clinical symptoms were shorter than control group;the NBNA score was higher than control group[MD= 3.68,95%CI(2.01,5.35),P<0.01];the normal rate of skull CT was higher than control group[MD=5.98,95%CI(3.04, 11.74),P<0.01].There were significant differences.There were no ARDs reports in two groups.CONCLUSION The results of Meta-analyses indicated that cattle encephalon glycoside and ignotin for patients with HIE is effective and has good safety. However,due to the quality of included studies,more sample size,high quality of RCTs are needed.
Keywords:
cattle encephalon glycoside and ignotin; hypoxic ischemic encephalopathy; HIE; randomized controlled trial; systematic review;
- DOI:
10.13286/j.cnki.chinhosppharmacyj.2014.01.17
- Series:
- Subject:
- Classification Code:
R722.1
- Mobile Reading
Read on your phone instantly
Step 1Scan QR Codes
"Mobile CNKI-CNKI Express" App
Step 2Open“CNKI Express”
and click the scan icon in the upper left corner of the homepage.
Step 3Scan QR Codes
Read this article on your phone.
- HTML
- CAJ Download
- PDF Download
Download the mobile appuse the app to scan this coderead the article.
Tips: Please download CAJViewer to view CAJ format full text.
Download: 706 Page: 53-58 Pagecount: 6 Size: 469K
Citation Network
Related Literature
- Similar Article
- Reader Recommendation
- Associated Author