子宫肌瘤动物模型构建方法的实验研究概况
李文刘新敏
中国中医科学院广安门医院北京中医药大学
Abstract: 子宫肌瘤是女性生殖器官最常见的良性肿瘤,其病因及发病机制尚不明确。动物实验是研究该病发病机制及临床前药物筛选的重要方法之一。国外子宫肌瘤动物模型有外源性性激素诱导模型、自发性模型、转基因小鼠模型和异种移植模型。国内多采用外源性性激素诱导模型,但在造模中给药的剂量、频率、时间不一致。本论文对国内外的各种造模方法进行了综述。
- DOI:
10.13283/j.cnki.xdfckjz.2014.11.022
- Series:
- Subject:
- Classification Code:
R737.33;R-332
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