Chinese Archives of Traditional Chinese Medicine. 2010, (05)

The Experimental Study on Influnce of the Method of Invigorating the Spleen and Kidney Benefiting Qi and Nourishing Yin on Hypoglycemic Mechanism and Pertention Ability of the Liver of Diabetes RatsChinese Full Text

XIE Ning1,WU Song1,LI Da-peng2,GUAN Hui-bo1(1.Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,Heilongjiang,China;2.Qinhuangdao Concer Hospital,Qinghuangdao 066004,Hebei,China)

Abstract: Objective:To observe the effect of invigorating the spleen and kidney beneifiting qi and nourishing yin on the prescription to STZ-DM diabetes for decreasing blood glucose and its mechanism.Methods:High-sugar high-fat diet for 4 weeks after the single intraperitoneal injection of STZ solution,manufacturing diabetic rat model,detection 10,20,30 days after treatment the changes in FBG were observed after treatment in each group in general,detection of liver glycogen,liver histopathology.Results:Delivery 30 days,the group can significantly reduce high blood sugar levels,compared with the effect of the treatment group significantly （P＜0.01）;After treatment,the high group in liver glycogen content is higher than the treatment group （P＜0.01）.liver tissue pathologye high treatment groups showed significant improvement.Conclusion:The method could improve the quality of life in rats,and the DM of rat’s FBG had been controlled;At the same time,increase the STZ-DM rat model of liver glycogen content,and on the STZ-DM rats has a protective role in liver.

Keywords：

diabetes mellitus; blood glucose; streptozotocin; liver;

DOI：
10.13193/j.archtcm.2010.05.19.xien.061
Series：
Subject：
Classification Code：
R285.5

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The Experimental Study on Influnce of the Method of Invigorating the Spleen and Kidney Benefiting Qi and Nourishing Yin on Hypoglycemic Mechanism and Pertention Ability of the Liver of Diabetes RatsChinese Full Text

XIE Ning1,WU Song1,LI Da-peng2,GUAN Hui-bo1(1.Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,Heilongjiang,China;2.Qinhuangdao Concer Hospital,Qinghuangdao 066004,Hebei,China)

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