痰瘀消胶囊对大鼠脑缺血再灌注TM、GMP-140的影响
张建荣杨学斌何锋赵骥
陕西中医学院中医临床医学院江苏省建湖县中医院陕西省博爱医院西安北环医院
Abstract: 目的:观察痰瘀消胶囊对脑缺血再灌注损伤(CRI)大鼠的治疗作用。方法:采用夹闭双侧颈总动脉45min后再通,制备CRI大鼠模型,分别用痰瘀消胶囊、血塞通、阿司匹林治疗,给药两周后,检测大鼠血浆血栓调解蛋白(TM)、血小板表面α颗粒膜蛋白140(GMP-140)含量。结果:该方能降低CRI大鼠血浆中TM、GMP-140的含量;并能改善大鼠神经功能缺损体征。结论:痰瘀消胶囊对CRI大鼠有治疗作用。
- DOI:
10.13192/j.ljtcm.2012.02.182.zhangjr.074
- Series:
- Subject:
- Classification Code:
R285.5
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