SDF-1/CXCR-4对内皮祖细胞生物学功能的影响
尹扬光黄岚
第三军医大学新桥医院心内科第三军医大学新桥医院心内科 重庆400037重庆400037
Abstract: 内皮祖细胞（EPC）移植或动员内源性EPC可加速损伤血管的再内皮化。基质细胞衍生因子-1（SDF-1）能通过其受体CXCR4促进骨髓干细胞向EPC方向分化,抑制EPC凋亡。升高外周血SDF-1浓度可动员EPC进入外周血。SDF-1/CXCR4系统在EPC迁移、捕获及归巢过程中起重要作用,参与促进缺血性血管生成。
Keywords：
- DOI：
10.13191/j.chj.2007.05.114.yinyg.002
- Series：
- Subject：
- Classification Code：
R329
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