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Effects of diltiazem on coronary spasm during percutaneous transluminal coronary angioplastyChinese Full Text

GA0 Feng~1,ZHOU Yi~2(1.Health Care Division,Security Bureau of Headquarters of the General Staff,Beijing 100017,China)

Abstract: AIM To investigate the effects of diltiazem on coronary spasm during percutaneous transluminal coronary angioplasty in patients with acute myocardial infarction.METHODS The catabatic rate of coronary spasm was evaluated from 39 patients undergoing percutaneous transluminal coronary angioplasty(PTCA) who had been treated with diltiazem or nitroglycerin.(RESULTS) In the group treated with diltiazem,the catabatic rate of coronary spasm was 85% and 15% respectively 20 s and 40 s after injection,and the total catabatic rate was 100%.In the group treated with nitroglycerin,the catabatic rate was 79% and 11% respectively 20 s and 40 s after injection,and the total catabatic rate was 89%.There was no significant difference between the two groups.No significant difference in arterial pressure and heart rate was found 1,3,5 and 10 min respectively after diltiazem treatment.(CONCLUSION) Diltiazem shares the same effects with nitroglycerin on coronary spasm during percutaneous transluminal coronary angioplasty in patients suffering from acute myocardial infarction.There are no serious negative chronotropic and hypotension after diltiazem treatment.
  • DOI:

    10.13191/j.chj.2006.04.96.gaof.029

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  • Classification Code:

    R542.22

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