Change of angiotensin Ⅱ in hypothalamus of rats exposed to infrasoundChinese Full Text

ZHAO Zhi-gang,CHEN Jing-zao,ZHANG Li-yan (Department of Radiation Medicine, Faculty of Preventive Medicine,Fourth Military Medical University, Xi’an, Shaanxi 710032,China)

Abstract: AIM: To observe the change of angiotensin Ⅱ （AngⅡ） in hypothalamus of rats exposed to infrasound. METHODS:The rats were exposed to infrasounds （frequence:16 Hz; acotustic pressure:130 dB and 90 dB）, for 1,7,14,and 21 d,2 h daily, then AngⅡ contents were measured 0.5,6,12,18,and 24 h after the exposure. RESULTS: AngⅡ varied regularly, increasing firstly,then decreasing, and increasing again,after rats exposed to infrasound either with 130 dB for 1,14 and 21 d or with 90 dB for 7 and 21 d. In rats exposed to infrasound with 130 dB for 7 d AngⅡ increased continuously. After the exposure to infrasound with 90 dB for 1 and 14 d, AngⅡ of rats presented on the peak curve, and 12 h after the group were exposed to infrasound for 14 d, no signficant difference was detected between the exposure and the control groups. CONCLUSION: The content of AngⅡ in the hypothalamus of rats affected by the infrasounds with different sound intensities and by different numbers of exposures was fluctuated.

Keywords：

infrasound; rat; hypothalamus; angiotensinⅡ;

DOI：
10.13191/j.chj.2003.04.7.zhaozhg.002
Series：
Subject：
Classification Code：
R363

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Change of angiotensin Ⅱ in hypothalamus of rats exposed to infrasoundChinese Full Text

ZHAO Zhi-gang,CHEN Jing-zao,ZHANG Li-yan (Department of Radiation Medicine, Faculty of Preventive Medicine,Fourth Military Medical University, Xi’an, Shaanxi 710032,China)

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