Knowledge Network Node
Chinese Heart Journal. 2001, (03)

Morphological study on implanted valved aortic homograft conduit of neonate rabbitChinese Full Text

CHEN Wen sheng, LIU Wei yong, WANG Gang, ZHU Hai long (Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an Shaanxi 710032, China)

Abstract: AIM: To observe the post implantation morphological changes in valved aortic homograft conduit（VAHC） of neonate rabbit. METHODS: The animal model of the VAHC was established via retroperitoneal pathway. Neonatal New Zealand rabbits（weight:150~200 g, n =24） were used as donors of the VAHCs, and young （0.9~1.2 kg, n =12） and adult rabbits （2.1~2 9 kg, n =12） as recipients. The specimens harvested 1 month and 6 months after the implantation were measured and studied under microscope. RESULTS: The intima of VAHCs was smooth and no emboli were found. The thicknesses of the walls in all the VAHCs, the lengths and diameters of the VAHCs in the young recipients 6 months post implantation increased significantly than those before the operation（ P ＜0.05）. The heights and free edge lengths of cusps in the VAHCs implanted in the 6 months were higher than those of the control VAHCs （ P ＜0.05）. Light microscopic examination of the explanted VAHCs revealed intimal and media proliferation, cellular infiltration and valvular thickening. The above changes were even more obvious in the adult recipients 6 months post implantation. CONCLUSION: The VAHCs of neonate rabbits implanted in the young rabbits can increase with the growth of recipients,which indicates that small VAHC may be applied clinically.
Keywords：

valved aortic homograft conduit; transplantation; morphology; neonate animal;

  • DOI：

    10.13191/j.chj.2001.03.13.chenwsh.004

  • Series：

  • Subject：

  • Classification Code：

    R654.2

  • Mobile Reading
    Read on your phone instantly
    Step 1

    Scan QR Codes

    "Mobile CNKI-CNKI Express" App

    Step 2

    Open“CNKI Express”

    and click the scan icon in the upper left corner of the homepage.

    Step 3

    Scan QR Codes

    Read this article on your phone.

  • HTML
  • CAJ Download
  • PDF Download

Download the mobile appuse the app to scan this coderead the article.

Tips: Please download CAJViewer to view CAJ format full text.

Download: 24 Page: 175-177 Pagecount: 3 Size: 73k

Related Literature
  • Similar Article
  • Reader Recommendation
  • Associated Author