Effect of the cardioactive recipe injection on hemodynamics in anesthetized open chest dogChinese Full Text
ZHANG Li, REN Ping, HUANG Xi ,GUO Wen yi, WANG Li li,WU Hu xiang Xijing Hospital,Fourth Military Medical University,Xi’an 710032,Shaanxi,China
Abstract: AIM: In order to study the hemodynamic changes after bolus atrial injection of the cardioactive recipe of LCH in anesthetized open chest dogs. METHOD: Heart rate ( HR), left ventricular systolic pressure (LVSP),peak derivative of left ventricular systolic pressure LVd p /d t max, coronary blood flow (CBF) were observed after bolus atrial injection by the dose of 0.3,0.6, 0.9, 1.2 g/kg, respectively. RESULTS: CR induced the decreases in HR,LVSP,+ LVd p /d t ( kPa/s), -LVd p /d t (kPa/s) and the increase in CBF, while low dose of CR has not any hemodynamic effects. CONCLUSION: The cardioactive recipe of LCH have siginificant negative inotropic and chronotropic effects.It also induces fast increase of CBF and the decrese of mAop.
- DOI:
10.13191/j.chj.2000.03.49.zhangl.021
- Series:
- Subject:
- Classification Code:
R285.5
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