Effect of external counter pulsation on plasma endothelin and tissue plasminogen activities in patients with coronary heart diseaseChinese Full Text
Wang Congxia 1,Sun Jichuan 1,Tian Qinghai 1,Ding Kangning 1,Zhang Jinhu 2 1 Department of Cardiology,Second Affiliated Hospital,Xi′an Medical University,Xi′an 710004 2 People′s Hospital of Shaanxi Province
Abstract: 40 patients with coronary heart disease treated by external counter pulsation(ECP) were divided into three groups:acute myocardial infarction(n=5),unstable angina pectoris(n=13),stable angina pectoris(n=22).Plasma endothelin 1(ET 1),tissue type plasminogen activator(t PA) and plasminogen activator inhibitor 1(PAI 1) were studied before and after ECP. The results showed that plasma ET 1 and PAI 1 decreased significantly while plasma t PA increased obviously after ECP. It is indicated that ECP treated coronary heart disease through changing levels of endothelium derived vasoactive substances besides hemodynamics and hemorrheology factors. So the new viewpoint is put forward about treating mechanisms of ECP for coronary heart disease.
- DOI:
10.13191/j.chj.1997.04.17.wangcx.006
- Series:
- Subject:
- Classification Code:
R541.4
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