1986 Volume 48 Issue 4 Pages 837-839
Decreased plasma insulin levels in lactating rats were restored by the treatment with CB-154, but at the same time, lactation ceased. Low plasma insulin levels in lactating rats were also restored by the removal of pups. This rise due to pups-removal was not prevented by prolactin administration. Plasma insulin lowered again with resumption of nursing. Thus, milk production presumably serves to suppress insulin secretion from B-cells.