A survey of viruses associated with feline respiratory diseases was conducted by virus isolation from swabs collected from cats visiting the University Veterinary Hospital and from apparently healthy laboratory cats in a medical school animal center. Twenty-nine caliciviruses and 2 herpesviruses were isolated from 29 of 65 cats with respiratory disease and 2 caliciviruses were from 2 of 49 cats with other diseases. From 50 laboratory cats 2 caliciviruses were also isolated.