A case of equine cryptorchidism with undetectable serum anti-Müllerian          hormone

Harutaka MURASE; Akihiro OCHI; Teruaki TOZAKI; Hironaga KAKOI; Tsogtgerel MUNKHTUUL; Shinjiro KURIMOTO; Fumio SATO; Tetsuro HADA

doi:10.1292/jvms.18-0057

Theriogenology

A case of equine cryptorchidism with undetectable serum anti-Müllerian hormone

Harutaka MURASE, Akihiro OCHI, Teruaki TOZAKI, Hironaga KAKOI, Tsogtgerel MUNKHTUUL, Shinjiro KURIMOTO, Fumio SATO, Tetsuro HADA

Author information

Harutaka MURASE
Equine Science Division, Hidaka Training and Research Center, Japan Racing Association, 535-1, Nishicha, Urakawa, Hokkaido 057-0171, Japan
Akihiro OCHI
Laboratory of Clinical Science and Pathobiology, Equine Research Institute, Japan Racing Association, 1400-4, Shiba, Shimotsuke, Tochigi 329-0412, Japan
Teruaki TOZAKI
Genetic Analysis Department, Laboratory of Racing Chemistry, 1731-2, Tsurutamachi, Utsunomiya, Tochigi 320-0851, Japan
Hironaga KAKOI
Genetic Analysis Department, Laboratory of Racing Chemistry, 1731-2, Tsurutamachi, Utsunomiya, Tochigi 320-0851, Japan
Tsogtgerel MUNKHTUUL
United Graduate School of Veterinary Sciences, Gifu University, 1-1, Yanagido, Gifu, Gifu 501-1193, Japan
Shinjiro KURIMOTO
Racehorse Hospital, Ritto Training Center, Japan Racing Association, 1028, Misono, Ritto, Shiga 520-3085, Japan
Fumio SATO
Equine Science Division, Hidaka Training and Research Center, Japan Racing Association, 535-1, Nishicha, Urakawa, Hokkaido 057-0171, Japan
Tetsuro HADA
Equine Science Division, Hidaka Training and Research Center, Japan Racing Association, 535-1, Nishicha, Urakawa, Hokkaido 057-0171, Japan

Keywords: anti-Müllerian hormone, cryptorchidism, monorchidism, stallion

JOURNAL OPEN ACCESS

2020 Volume 82 Issue 2 Pages 209-211

DOI https://doi.org/10.1292/jvms.18-0057

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Details

Abstract

Serum anti-Müllerian hormone (AMH), a marker of equine cryptorchidism, is detectable in intact and cryptorchid stallions but not in geldings because it is secreted from Sertoli cells. A 4-year-old uncastrated Thoroughbred racehorse had no visible testes; therefore, the horse was considered a bilateral cryptorchidism. However, the serum AMH was undetectable (<0.08 ng/ml). Human chorionic gonadotrophin (hCG) stimulating test result indicated that the horse was a gelding. The results of sex chromosomal analysis and sequence analysis of SRY gene suggested that the horse was a genetically-intact stallion (X/Y). Only one small degenerative testis was present in the abdominal cavity. The reasons of undetectable serum AMH levels and negative response to hCG stimulation might be low numbers of Sertoli and Leydig cells. This study reports a case of serum AMH-undetectable cryptorchid stallion.

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