Pathology
Uterine Adenocarcinoma with Prominent Desmoplasia in a Geriatric Miniature Pig
2010 Volume 72 Issue 2 Pages 253-256
Details
2010 Volume 72 Issue 2 Pages 253-256
A 10-year-old miniature sow was died, showing inappetence and weight loss. Grossly, neoplastic enlargement of the uterus was found. Histopathologically, the lesions consisted of acinar, ductular and cystic proliferations of mono- and multilayered epithelial cells; these cells reacted immunohistochemically strongly with three different cytokeratin antibodies, and occasionally to vimentin. Myofibroblastic desmoplastic cells, positive to α-smooth muscle actin, were present among neoplastic cells. Metastatic lesions were seen in the lungs and liver. Based on these findings, a diagnosis of uterine adenocarcinoma with marked desmoplasia was made. This case is the second report of uterine adenocarcinoma in the miniature pig.
Journal of The Japanese Society of Veterinary Science
