J Korean Fract Soc. 2012 Jan;25(1):1-7. Korean.
Published online Jan 31, 2012.
Copyright © 2012 The Korean Fracture Society
Original Article

Risk Factors of Periprosthetic Fracture after Total Knee Arthroplasty

Ju-Young Shin, M.D., Hyung-Jun Kim, M.D., Seung-Han Cha, M.D. and Dong-Heon Kim, M.D.
    • Department of Orthopaedic Surgery, College of Medicine, Konkuk University, Chungju, Korea.
Received March 01, 2011; Revised May 31, 2011; Accepted November 22, 2011.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the incidence rate and risk factors for periprosthetic fracture after total knee replacement (TKR).

Materials and Methods

We carried out a retrospective case-control study of 596 patients (951 knees) who underwent TKR between 1999 and 2006 and who were followed up over 36 months. We classified patients into group I (study group) and group II (control group). We subdivided risk factors as pre-operative, intra-operative, and post-operative factors. Age, osteoporosis, revision arthroplasty, CVA, and alcohol dependence were categorized as pre-operative factors; anterior femoral notching and prosthetic types (mobile, fixed, and load-bearing) were considered intra-operative factors; and post-operative activity level was classified as a post-operative factor. We obtained information from the patients' charts, X-ray film, and telephone interviews.

Results

The overall incidence rate was 2.25%; 3 patients were male, and 18 were female (14.28% and 85.72%, respectively). Old age (p<0.01, odds ratio=1.14), osteoporosis (p=0.01, odds ratio=4.74), revision arthroplasty (p=0.01, odds ratio=7.46), CVA (p=0.02, odds ratio=8.55), and alcohol dependence (p=0.03, odds ratio=44.54) were statistically significant among the pre-operative factors. Among the intra-operative factors, anterior femoral notching (p<0.01, odds ratio=11.74) was significant, and continued heavy labor (p<0.01, odds ratio=8.14) was significant among the post-operative factors.

Conclusion

We concluded that old age, osteoporosis, revision arthroplasty, comorbidity related with falling down, anterior femoral notching, and continued heavy labor were associated with periprosthetic fracture after TKR.

Keywords
Risk factor; Periprosthetic fracture; Total knee replacement

Figures

Fig. 1
(A) Tansverse sections of the distal femur showing notching.

(B) Sagittal section of the distal femur demonstrating grade III and IV notching.

Tables

Table 1
UCLA activity-level rating system

Table 2
The cause of periprosthetic supracondylar fracture

Table 3
Summary of patient's data

Table 4
Risk factors by Multi-variable logistic regression

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