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Bone deformity showing a deep coronoid notch of the mandible in a patient with neurofibromatosis type 1

Department of Oral and Maxillofacial Radiology, Field of Tumor Biology, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan

*Correspondence to: Miki Hisatomi, Department of Oral and Maxillofacial Radiology, Field of Tumor Biology, Graduate School of Medicine and Dentistry, Okayama University, 2-5-1, Shikata-cho, Okayama-city, Okayama, 700-8525, Japan; E-mail: tomi{at}md.okayama-u.ac.jp

Received 2 December 2004; revised 8 March 2005; accepted 17 April 2005

We present a case of a 10-year-old girl with neurofibromatosis type 1 related skeletal dysplasia. In the present case, a unilocular radiolucency at the left coronoid notch visible on a panoramic radiograph was suspected to be a neurofibroma. However, only the presence of bone deformities was observed on CT. Fat-like tissue adjacent to the bone deformities inside the left mandibular ramus was revealed, and the presence of neurofibroma was unequivocally denied on the MR images. However, biopsy of the lesion suggested neurofibroma. The diagnostic imaging 18 months after the first visit did not revealed a tumourous mass. However, careful follow up is required even though we could not prove the presence the lesion on the basis of imaging.

Keywords: neurofibromatosis type 1; Von Recklinghausen's disease; mandibular foramen; neurofibroma

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