Case Reports
Severe Thrombocytopenia Caused by Digitoxin Intoxication in a Patient With Heart Failure Associated With Sjögren’s Syndrome
2000 Volume 64 Issue 4 Pages 309-311
Details
2000 Volume 64 Issue 4 Pages 309-311
Congestive heart failure (CHF) related to Sjögren’s syndrome is extremely rare. This report concerns a patient who presented with CHF and severe thrombocytopenia (5, 000/μl). Serum concentrations of K, Mg and digitoxin were 3.2mmol/L, 1.4mg/L and 57.2ng/ml, respectively. Digitoxin intoxication was evident, seemingly evoked by hypokalemia, hypomagnesemia, hepatorenal dysfunction and hypothyroidism. The severe thrombocytopenia was considered to have been caused by this intoxication, as it disappeared soon after the digitoxin was discontinued and potassium was supplemented.
