Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Two New Xanthones Isolated from the Stem Bark of Garcinia lancilimba
Nian-Yun YangQuan-Bin HanXin-Wei CaoChun-Feng QiaoJing-Zheng SongShi-Lin ChenDa-Jian YangHillary YiuHong-Xi Xu
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2007 Volume 55 Issue 6 Pages 950-952

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Abstract

Two new xanthones, 1,5,6-trihydroxy-6′,6′-dimethyl-2H-pyrano(2′,3′:3,4)-2-(3-methylbut-2-enyl)xanthone (1) and 1,6,7-trihydroxy-6′,6′-dimethyl-2H-pyrano(2′,3′:3,2)-4-(3-methylbut-2-enyl)xanthone (2), have been isolated from the stem bark of Garcinia lancilimba (Guttiferae), together with six known xanthones. Their structures were identified on the basis of extensive spectral evidence including detailed 2D NMR and HR-MS data. Two new compounds showed moderate inhibitory effect on human breast cancer MDA-MB-435S cell line.

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© 2007 The Pharmaceutical Society of Japan
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