Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Diastereomeric Diterpenes from Coleus blumei
Consolacion Y. RAGASAVilma F. TEMPLORAJohn A. RIDEOUT
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2001 Volume 49 Issue 7 Pages 927-929

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Abstract

The chloroform extract of the air-dried leaves of Coleus blumei afforded a mixture of diastereomers of a new abietane type diterpene whose structures were elucidated by extensive one and two dimensional (1D, 2D) NMR and mass spectrometry. Acetylation of the mixture afforded a single compound. Antimicrobial tests on the diterpene indicate that it is active against Bacillus subtilis, Pseudomonas aeruginosa and Candida albicans.

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© 2001 The Pharmaceutical Society of Japan
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