Synthesis and Anti-peptic Activity of Compounds Related to the Metabolites of Sodium 3-Ethyl-7-isopropyl-1-azulenesulfonate (KT1-32)

Takashi YANAGISAWA; Kazuhiro KOSAKAI; Chikako IZAWA; Tsuyoshi TOMIYAMA; Masafumi YASUNAMI

doi:10.1248/cpb.39.2429

Takashi YANAGISAWA, Kazuhiro KOSAKAI, Chikako IZAWA, Tsuyoshi TOMIYAMA, Masafumi YASUNAMI

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Keywords: metabolite, sodium 3-ethyl-7-isopropyl-1-azulenesulfonate (KT1-32), anti-peptic activity

JOURNAL FREE ACCESS

1991 Volume 39 Issue 9 Pages 2429-2432

DOI https://doi.org/10.1248/cpb.39.2429

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Abstract

The metabolites of sodium 3-ethyl-7-isopropyl-1-azulenesulfonate (KT1-32, 1), a candidate as an anti-ulcer drug, and related compounds were synthesized. The effects of the compounds on anti-peptic activity were determined as compared to that of 1.

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