Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Antitumor Substances. III. Syntheses of Bis(methanesulphonylthio)alkanes
Seigoro Hayashi, Hiroshi Ueki, Seiko Harano, Junko Komiya, Susumu Iyama, Kazunobu Harano, Katsuaki Miyata, Kunihiro Niigata, Yoshiro Yonemura
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1964 Volume 12 Issue 11 Pages 1271-1276

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Abstract

Dimethanesulphonylthioalkanes and analogous compounds were synthesized by the reaction of corresponding sodium thiosulphonate and appropriate dibromide to test the carcinostatic activity compaed with Myleran. It was found that some of these compounds inhibited pronouncedly the growth of the solid tumor produced by Ehrlich ascites carcinoma cells.

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© The Pharmaceutical Society of Japan
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