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From the Departments of Neurology (A.A.R., N.M.-K.), University of Miami School of Medicine, Miami, FL; Department of Neurology (B.V.M., E.F.M.W.) and Division of Biostatistics (W.R.B.), Mayo Clinic, Rochester, MN; Departments of Radiology (A.R.Z.) and Neurology (A.R.Z., M.N.D.) and Neurology/Neurosurgery Intensive Care Unit (M.N.D.), Washington University, St. Louis.
Address correspondence and reprint requests to Dr. Alejandro A. Rabinstein, 200 First Street SW, Mayo Clinic, W8, Rochester, MN 55905; e-mail: rabinstein.alejandro{at}mayo.edu
The authors reviewed 42 consecutive cases of decompressive hemicraniectomy after hemispheric ischemic stroke to assess predictors of outcome. On univariate analysis, advanced age and history of hypertension were significantly associated with unfavorable outcome, whereas thrombolysis was protective. Side of infarction, pupillary nonreactivity, degree of preoperative midline shift, and timing of surgery did not predict outcome. On multivariate analysis, older age independently predicted poor recovery (odds ratio 2.9 per 10-year increase in age).
Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the September 12 issue to find the title link for this article.
Disclosure: The authors report no conflicts of interest.
Received December 27, 2005. Accepted in final form May 9, 2006.
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