ABSTRACT

Life expectancy is increasing, with a consequent increase in the cognitive disorders of old age. Treating these as early as identifiable would seem an appropriate course of action. Mild cognitive impairment (MCI) represents a stage where people have the early neuropathology of dementia, particularly Alzheimer’s disease (AD), but do not have sufficient symptoms to fulfil current clinical criteria. Transition to dementia is frequent, raising questions as to whether this is a new nosology or the earliest diagnosable point of the more common neurodegenerative disorders.